Research Experience

Albert Einstein College of Medicine, Bronx, NY

Neuroscience Researcher (Postdoctoral Fellow)  2015-2020

Interplay between Chaperone Mediated Autophagy and Parkinson’s Disease

  • Leading of a team of 3 scientists to investigate genetic and chemical modulation of Chaperone-Mediated Autophagy in Parkinson’s Disease mice models as a therapeutic approach to improve age-related neurodegeneration
  • Gain novel experimental skills and techniques such as mice colony maintenance, cryo-sectioning, immunohistochemistry, mice survival surgeries, brain slice culturing in order to successfully lead this project
  • Design, execute and investigate lysosomal role of LRRK2 protein by performing various lysosomal assays and analysis, orchestrating a collaboration with a biotech firm specializes in Parkinson Disease Therapeutics
  • Regularly presented data and posters on team meetings, seminars and consortium meetings; published 1 review article and currently drafting a research article manuscript
  • Establish novel techniques and train laboratory personnel for performing various cell biology protocols
  • Compile and draft various experimental protocols

 Hoffmann-La Roche Innovation Center / Albert Einstein College of Medicine Bronx, NY

Cell Biology Researcher (Roche Postdoctoral Research Fellow) 2015-2017

Cellular trafficking of antisense oligonucleotides

  • Awarded funding for competitive innovative research for two years (Roche Postdoctoral Fellowship Program)
  • Designed and executed complex in vitro assays to analyze role of modulating different autophagy pathways on trafficking of antisense oligonucleotides for potential treatments of genetic and neurodegenerative diseases
  • Presented data on quarterly progress meetings to Roche mentor for two years with written deliverable reports
  • Submitted research results as a manuscript to Nucleic Acids Research, highly prestigious journal of the field

Sabanci University, Istanbul, Turkey

Molecular Biology Researcher (Graduate Student) 2010-2015

microRNA regulation of autophagy in health and disease

  • Pioneered discovery of novel microRNAs that regulate autophagy; a cellular mechanism that removes unnecessary or dysfunctional cellular components, investigated potential implications of these molecules in cancer therapeutics
  • Performed extensive in vitro experiments to understand in-depth characterizations of miR-376 family and miR-181a on regulation of autophagy, published 3 research, 3 review articles, 1 book chapter, area expertise proven by 505 citations
  • Trained junior graduate students and laboratory personnel, ordered lab supplies while negotiating with suppliers to maintain the lab budget, drafted various experimental protocols as standard operating procedures (SOP)
  • Presented scientific findings to diverse audiences at both regional and international conferences, was recognized for excellent oral communication

Karolinska Institute, Stockholm, Sweden

Visiting Research Scholar (Summer Intern for three months) 2009

Characterization of human natural killer cells with flow cytometry analysis

  • Optimized novel protocols for immunophenotyping of human natural killer cells to analyze and predict possible natural killer cell mediated anti‐tumor responses
  • Gained hands-on expertise on molecular biology methods including mammalian cell culture, transfection, recombinant DNA technology, flow cytometry (FACS) analysis, familiarized with European research culture and environment