PUBLICATIONS-Selected

x Corresponding author, * First authors with equal contribution.

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Selected articles (Basic sciences)  

1) Karakas HE*, Kim JY*, Park  J, Oh JM, Choi Y, Gozuacik Dx, Cho YKx. A microfluidic chip for screening individual cancer cells via eavesdropping on autophagy inducing crosstalk in the stroma niche. Scientific Reports, 2017. 7(1):2050. doi: 10.1038/s41598-017-02172-7. (Impact factor: 5.2. Times cited: ). Link

2) Erbil S, Oral O*, Mitou G*, Cenk Kig, Durmaz-Timucin E, Guven-Maiorov E, Gulacti F, Gokce G, Dengjel J, Sezerman OU, Gozuacik Dx. RACK1 is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy. The Journal of Biological Chemistry (JBC), 2016, 291(32):16753-65. (Impact factor: 4.6. Times cited: ). Link

3) Bayraktar O, Oral O*, Kocaturk NM*, Akkoc Y, Eberhart K, Kosar A, Gozuacik Dx. IBMPFD Disease-Causing Mutant VCP/p97 Proteins Are Targets of Autophagic-Lysosomal Degradation. PLoS One, 2016, 11(10): e0164864. Doi: 10.1371/journal.pone.0164864. (Impact factor: 4. Times cited: ). Link

4) Tekirdag AK*, Korkmaz G*, Ozturk DG, Agami R, Gozuacik Dx. miR-181a regulates starvation- and rapamycin-induced autophagy through targeting of ATG5. Autophagy, 2013 Mar;9(3):374-85. (Impact factor: 12. Times cited: 49). Link

5) Korkmaz G, le Sage C, Tekirdag AK, Agami R, Gozuacik Dx. miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. Autophagy, 2012 February; 8(2): 165 – 176. (Impact factor: 12. Times cited: 97). Link

6) Oral O*,  Oz-Arslan D*, Itah Z, Naghavi A, Deveci R, Karacali S, Gozuacik Dx. Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death. Apoptosis, 2012 Aug; 17(8):810-20. (Impact factor: 4. Times cited: 49). Link 

7) Gozuacik D, Bialik S, Raveh T, Mitou G, Shohat G, Sabanay H, Mizushima N, Yoshimori T, Kimchi A. DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death and Differentiation, 2008 15(12): 1875-86.  (Impact factor: 9. Times cited: 137). Link

8) Llambi F, Calheiros F, Gozuacik D, Pays L, Del Rio G, Kimchi A, Mehlen P. The dependence receptor UNC5H2 mediates apoptosis through DAP kinase. EMBO Journal, 2005 Mar 23;24(6):1192-201. (Impact factor: 9.8. Times cited: 101).

9) Gozuacik D, ChamiM, Murakami Y, FaivreJ, LagorceD, Poch O, Biermann O, Knippers R, BréchotC, Paterlini-BréchotP. Identification and functional characterization of a new member of the human Mcm protein family: hMcm8. Nucleic Acids Research, 2003 Jan 15;31(2):570-9. (Impact factor: 9.2. Times cited: 63).

10) Chami M*, Gozuacik D*, Lagorce D, Brini M, Falson P, Peaucellier G, Pinton P, Lecoeur H, Gougeon ML, le Maire M, Rizzuto R, Brechot C, Paterlini-Brechot P. SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis. Journal of Cell Biology (JCB), 2001 Jun 11;153(6):1301-14. (Impact factor: 9.8. Times cited: 45)

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Selected review articles

1) Gozuacik Dx, Akkoc Y, Ozturk DG, Kocak M. Autophagy, MicroRNAs and Cancer. In the special issue: Self-eating on demand: Autophagy in Cancer and Cancer Therapy (Eds. Agostinis P and Lane J). Frontiers in Oncology, 2017. 7:65. doi: 10.3389/fonc.2017.00065. Link

2) Ozlem Oralx, Yunus Akkoc, Gozuacik D. Physiological and Pathological Significance of Molecular Cross-talk Between Autophagy and Apoptosis. Histology and Histopathology, 2015 Dec 18:11714. Link

3) Gozuacik Dx, Yagci-Acar HF, Akkoc Y, Kosar A, Dogan-Ekici AI, Ekici S. Anticancer use of nanoparticles as nucleic acid carriers. Journal of Biomedical Nanotechnology, 2014, September; 10(9): 1751-1783. Link

4) Tekirdag KA, Ozturk DG, Gozuacik Dx. Alterations in autophagic-lysosomal potential during ageing and neurological diseases: The miRNA perspective. Current Pathobiology Reports, 2013 December 2013, Volume 1, Issue 4, pp 247-261. Link

5) Gozuacik D and Kimchi A. Autophagy and cell death. Current Topics in Developmental Biology, 2007 78:217-45. 

6) Gozuacik D and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene, 2004 Apr 12;23(16):2891-906. Review.

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Selected book chapters 

1) Gozuacik Dx and Kig C. Cell death and autophagy: A historical perspective. In the book: Cell Death 1994-2014. Richard Lockshin and Zahra Zakeri (Eds.). An Anniversary Publication of the International Cell Death Society (ICDS). 2015. Link

2) Tekirdag KA, Ozturk DG, Gozuacik Dx. Regulation of autophagy by miRNAs. In the book: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, and Infection. Hayat MA (Ed.). Elsevier Academic Press. 2015. ISBN: 9780128010327, Book chapter. Link

3) Arachiche A and Gozuacik Dx. Autophagy in health and disease. In the book: Toxicity and autophagy in neurodegenerative disorders. Jose Manuel Fuentes (Ed.). Springer Publishing. 2015. ISBN: 978-3-319-13938-8, Book chapter. Link

4) Eberhart K, Oral O, Gozuacik Dx. Induction of autophagic cell death by anticancer agents. pp 179-202. In the book: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, and Infection. Hayat MA (Ed.). Elsevier Academic Press. 2013. ISBN: 9780124055308, Book chapter. Link

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Selected articles (Biomedical sciences)

1) Ozbey A, Karimzadehkhouei M, Akgonul S, Gozuacik D and Kosar Ax. Inertial Focusing of Microparticles in Curvilinear Microchannels (Circulating Tumor Cell (CTC) isolation biochip model). Scientific Reports, 2016, 6: 38809. (Impact factor: 5.2. Times cited: ). Link

2) Demir F, Hocaoglu I,Ozturk DG, Gozuacik D, Kiraz A, Yagci Acar Hx. Highly Luminescent and Cytocompatible Cationic Ag2S NIR-emitting Quantum Dots for Optical Imaging and Gene Transfection. Nanoscale, 2015, DOI: 10.1039/C5NR00189G. (Impact factor: 7.4. Times cited: 4). Link

3) Kucukgul C, Ozler SB, Inci I, Karakas E, Irmak S, Gozuacik D, Taralp A, Koc B. 3D Bioprinting of Biomimetic Aortic Vascular Constructs with Self-Supporting Cells. Biotechnology and Bioengineering, 2014 Nov 11. doi: 10.1002/bit.25493. (Impact factor: 4.2. Times cited: 3). Link

4) Itah Z*, Oral O*, Perk OY, Sesen M, Demir E, Erbil S, Dogan-Ekici AI, Ekici S, Kosar A, Gozuacik Dx. Hydrodynamic cavitation kills prostate cells and ablates benign prostatic hyperplasia tissue. Experimental Biology and Medicine, 2013 November; 238(11): 1242-1250. (Impact factor: 2.54. Times cited: 4). Link

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For a full CV of DG in PDF format click here.

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