PUBLICATIONS-Selected

x Corresponding author, * First authors with equal contribution.

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Selected articles (Basic sciences)  

1) Ozturk DG, Kocak M , Akcay A, Kinoglu K, Kara E, Buyuk Y, Kazan H and Gozuacik Dx. MITF/MIR211 axis is a novel autophagy amplifier system during cellular stress. Autophagy, 2018. In press.

2) Karakas HE*, Kim JY*, Park  J, Oh JM, Choi Y, Gozuacik Dx, Cho YKx. A microfluidic chip for screening individual cancer cells via eavesdropping on autophagy inducing crosstalk in the stroma niche. Scientific Reports, 2017. 7(1):2050. doi: 10.1038/s41598-017-02172-7. (Impact factor: 5.2. Times cited: ). Link

3) Erbil S, Oral O*, Mitou G*, Cenk Kig, Durmaz-Timucin E, Guven-Maiorov E, Gulacti F, Gokce G, Dengjel J, Sezerman OU, Gozuacik Dx. RACK1 is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy. The Journal of Biological Chemistry (JBC), 2016, 291(32):16753-65. (Impact factor: 4.6. Times cited: 2). Link

4) Bayraktar O, Oral O*, Kocaturk NM*, Akkoc Y, Eberhart K, Kosar A, Gozuacik Dx. IBMPFD Disease-Causing Mutant VCP/p97 Proteins Are Targets of Autophagic-Lysosomal Degradation. PLoS One, 2016, 11(10): e0164864. Doi: 10.1371/journal.pone.0164864. (Impact factor: 4. Times cited: 2). Link

5) Tekirdag AK*, Korkmaz G*, Ozturk DG, Agami R, Gozuacik Dx. MIR181A regulates starvation- and rapamycin-induced autophagy through targeting of ATG5. Autophagy, 2013 Mar;9(3):374-85. (Impact factor: 12. Times cited: 68). Link

6) Korkmaz G, le Sage C, Tekirdag AK, Agami R, Gozuacik Dx. MIR376B controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. Autophagy, 2012 February; 8(2): 165 – 176. (Impact factor: 12. Times cited: 110). Link

7) Oral O*,  Oz-Arslan D*, Itah Z, Naghavi A, Deveci R, Karacali S, Gozuacik Dx. Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death. Apoptosis, 2012 Aug; 17(8):810-20. (Impact factor: 4. Times cited: 58). Link 

8) Gozuacik D, Bialik S, Raveh T, Mitou G, Shohat G, Sabanay H, Mizushima N, Yoshimori T, Kimchi Ax. DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death and Differentiation, 2008 15(12): 1875-86.  (Impact factor: 9. Times cited: 146). Link

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Selected articles (Biomedical sciences)

1) Motezakker A, Sadaghiani AK, Akkoc A, Semsari Parapari S, Gozuacik D, Kosar Ax. Surface modifications for phase change cooling applications via crenarchaeon Sulfolobus solfataricus P2 biocoatings. Scientific Reports, 2017, 7 (17891). doi:10.1038/s41598-017-18192-2. (Impact factor: 5.2. Times cited: ). Link

2) Ozbey A, Karimzadehkhouei M, Akgonul S, Gozuacik D and Kosar Ax. Inertial Focusing of Microparticles in Curvilinear Microchannels (Circulating Tumor Cell (CTC) isolation biochip model). Scientific Reports, 2016, 6: 38809. (Impact factor: 5.2. Times cited: ). Link

3) Yar Y, Khodadust R, Akkoc Y, Utkur M, Saritas EU, Gozuacik D, Yagci Acar Hx. Development of Tailored SPION-PNIPAM Nanoparticles by ATRP for Dually Responsive Doxorubicin Delivery and MR Imaging. Journal of Materials Chemistry B, 2018, 6, 289 – 300. (Impact factor: 4.54. Times cited: ). Link

4) Demir F, Hocaoglu I,Ozturk DG, Gozuacik D, Kiraz A, Yagci Acar Hx. Highly Luminescent and Cytocompatible Cationic Ag2S NIR-emitting Quantum Dots for Optical Imaging and Gene Transfection. Nanoscale, 2015, DOI: 10.1039/C5NR00189G. (Impact factor: 7.36. Times cited: ). Link

5) Itah Z*, Oral O*, Perk OY, Sesen M, Demir E, Erbil S, Dogan-Ekici AI, Ekici S, Kosar A, Gozuacik Dx. Hydrodynamic cavitation kills prostate cells and ablates benign prostatic hyperplasia tissue. Experimental Biology and Medicine, 2013 November; 238(11): 1242-1250. (Impact factor: 3. Times cited: ). Link

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Selected review articles

1) Ozturk DG, Kocak M, Gozuacik Dx. Cloning of Autophagy-Related MicroRNAs. Methods Mol Biol. 2017 Oct 12. doi: 10.1007/7651_2017_83. Link 

2) Gozuacik Dx, Akkoc Y, Ozturk DG, Kocak M. Autophagy, MicroRNAs and Cancer. In the special issue: Self-eating on demand: Autophagy in Cancer and Cancer Therapy (Eds. Agostinis P and Lane J). Frontiers in Oncology, 2017. 7:65. doi: 10.3389/fonc.2017.00065. Link

3) Ozlem Oralx, Yunus Akkoc, Gozuacik D. Physiological and Pathological Significance of Molecular Cross-talk Between Autophagy and Apoptosis. Histology and Histopathology, 2015 Dec 18:11714. Link

4) Gozuacik Dx, Yagci-Acar HF, Akkoc Y, Kosar A, Dogan-Ekici AI, Ekici S. Anticancer use of nanoparticles as nucleic acid carriers. Journal of Biomedical Nanotechnology, 2014, September; 10(9): 1751-1783. Link

5) Tekirdag KA, Ozturk DG, Gozuacik Dx. Alterations in autophagic-lysosomal potential during ageing and neurological diseases: The miRNA perspective. Current Pathobiology Reports, 2013 December 2013, Volume 1, Issue 4, pp 247-261. Link

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Selected book chapters 

1) Gozuacik Dx and Kig C. Cell death and autophagy: A historical perspective. In the book: Cell Death 1994-2014. Richard Lockshin and Zahra Zakeri (Eds.). An Anniversary Publication of the International Cell Death Society (ICDS). 2015. Link

2) Tekirdag KA, Ozturk DG, Gozuacik Dx. Regulation of autophagy by miRNAs. In the book: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, and Infection. Hayat MA (Ed.). Elsevier Academic Press. 2015. ISBN: 9780128010327, Book chapter. Link

3) Arachiche A and Gozuacik Dx. Autophagy in health and disease. In the book: Toxicity and autophagy in neurodegenerative disorders. Jose Manuel Fuentes (Ed.). Springer Publishing. 2015. ISBN: 978-3-319-13938-8, Book chapter. Link

4) Eberhart K, Oral O, Gozuacik Dx. Induction of autophagic cell death by anticancer agents. pp 179-202. In the book: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, and Infection. Hayat MA (Ed.). Elsevier Academic Press. 2013. ISBN: 9780124055308, Book chapter. Link

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Keywords: What is autophagy? Otofaji nedir?