PROJECTS & EXPERIENCES

PROJECTS

  • 2017-2018
    • Investigation of drug resistance mechanisms for a new generation antiandrogen prostate cancer drug  Enzalutamide using advanced molecular dynamics simulation techniques
    • Sefer Baday, Behzad Aslani Avilaq, Burak Islek
    • funded by TUBITAK Career Development Program (3501)
  • 2016-2018
    • User Friendly Analysis Platform for DNA Sequencing
    • Burak Islek, Ozkan Ozdemir, Aycan Adal)
    • received capital  support within the scope of TUBITAK 1512 Entrepreneurship Multi-Phase (Individual Young Enterprise) Program
  • 2014-2017
    • Analyzing hRgr Gene Expression Levels in Subtypes of T cell Malignancies in Leukemic Patients
    • Burak Islek, Zeynep Karakas, Teoman Soysal, Rafi Suzme, Ugur Ozbek, Burcak  Vural
    • funded by TUBITAK Repatriation Research Scholarship Program (2232)-Master Thesis
  • 2014-2015
    • Whole-Genome Analysis with high-risk acute leukemia patients
    • Yucel Erbilgin, Burak Islek
    • funded by TUBITAK 1002 Short Term R&D Funding Program

EXPERIENCES

  • 2016-ongoing
    • Project & company direction
    • GENESIST R&D / ITU ARI TECHNOPARK
  • 2017-2018
    • ISTANBUL TECHNICAL UNIVERSITY
    • Institute of Informatics / High Performance Computing Laboratory
    • Research Areas: Computer-aided drug design, Biomolecule modelling and Simulation, Protein-ligand interactions
  • 2013-2017
    • ISTANBUL UNIVERSITY
    • Research Institute for Experimental Medicine (DETAE) / Hematology Lab.
    • Research Areas: Affymetrix Genechip Array (microarray gene expression analysis via R) , Sanger sequencing and Next Generation sequencing in pediatric patients with leukemia & lymphoma, pathophysiology of genetics & blood disorders, molecular dynamics & and gene interactions in cancer pathways
  • 2009 – 2011
    • KOC UNIVERSITY
    • Department of Chemical & Biological Engineering / Computational and Quantitative Biology Lab.
    • Research areas: Drug designing, docking strategies, protein-protein & protein-ligand interactions