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  1. Bodur C, Karakas B, Timucin AC, Tezil T, Basaga H. (2015) AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins, Molecular Carcinogenesis  doi: 10.1002/mc.22411.
  2. Tezil, T., and Basaga, H. (2014) Modulation of Cell Death in Age-Related Diseases, Current pharmaceutical design 20, 3052-3067.
  3. Grossi, V., Peserico, A., Tezil, T., and Simone, C. (2014) p38 alpha MAPK pathway: A key factor in colorectal cancer therapy and chemoresistance, World J Gastroentero 20, 9744-9758.
  4. Germani, A., Matrone, A., Grossi, V., Peserico, A., Sanese, P., Liuzzi, M., Palermo, R., Murzilli, S., Campese, A. F., Ingravallo, G., Canettieri, G., Tezil, T., and Simone, C. (2014) Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38alpha modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A, Cancer letters 344, 110-118.
  5. Tezil, T., Bodur, C., Kutuk, O., and Basaga, H. (2012) IKK-beta mediates chemoresistance by sequestering FOXO3; A critical factor for cell survival and death, Cellular signalling 24, 1361-1368.
  6. Bodur, C., Kutuk, O., Tezil, T., and Basaga, H. (2012) Inactivation of Bcl-2 through I kappa B kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE), Journal of cellular physiology 227, 3556-3565.
  7. Arisan, E. D., Kutuk, O., Tezil, T., Bodur, C., Telci, D., and Basaga, H. (2010) Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells, Breast cancer research and treatment 119, 271-281.
  8. Kutuk, O., Arisan, E. D., Tezil, T., Shoshan, M. C., and Basaga, H. (2009) Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation, Carcinogenesis 30, 1517-1527.


  1. Grossi V, Forte G, Peserico A, Tezil T, Loconte D, Bagnulo R, Resta N, Simone C, The G allele of FOXO3 RS2802292 SNP creates an HSF1-binding site which regulates FoxO3A expression, XVII Congresso Nazionale SIGU, 21-24 October 2015, Rimini, Italy.
  2. Celestini V, Tezil T, Peserico A, Simone C, SIRT3-dependent deacetylation of mitochondrial FoxO3A regulates colorectal cancer cell fate. PhD Students Meeting, Mario Negri Institute, 9-10 July 2015, Milan, Italy.
  3. Peserico A, Grossi V, Tezil T, Haigis MC, Villani G, Puri PL, Sartorelli V and Simone C. A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels. Cell Symposia, Mitochondria: from Signaling to Disease, 5-7 May 2013, Lisbon, Portugal.
  4. Tezil T, Celestini V, Grossi V, Peserico A, Simone C. Mitochondrial FoxO3A: a trojan horse to reverse cancer-specific metabolism. XVI Congresso Nazionale SIGU, 25-28 September 2013, Roma, Italy.
  5. Celestini V, Tezil T, Grossi V, Peserico A, Simone C. The FoxO3A/Sirt3 mitochondrial complex regulates energy balance in CRC cells. XVI Congresso Nazionale SIGU, 25-28 September 2013, Roma, Italy.
  6. Peserico A, Sanese P, Germani A, Di Virgilio V, Celestini V, Martelli N, Tezil T, Simone C. SMYD3 regulates the S/G2 transition in colorectal cancer (CRC) cells. XVI Congresso Nazionale SIGU, 25-28 September 2013, Roma, Italy.
  7. Tezil T and Basaga H, “The regulation of FOXO3 by IKK-beta in apoptosis and autophagy”. ECDO, 14-17 Sep 2012, Rome, Italy.
  8. Tezil T and Basaga H, “The role of FOXO3a and IKK in chemotherapeutic drug resistance/sensitivity in breast cancer cell lines”. Sixth EWCD, 1-6 June 2008, Hauenstein, Germany.
  9. Ates, Y.O. Tezil, T., Basaga, H. Effect of N-acetyl L-cysteine pretreatment on the apoptotic response of HCT 116 cells induced by Cisplatin administration. SFRR-E Free Radical Summer School, 2008, Spetses Island, Greece.
  10. Ates, Y.O., Tezil, T., and Basaga, H. (2008) Effect of the antioxidant N-acetyl-L-cysteine pretreatment on the apoptotic response of HCT 116 p53 wild type and knockout colon carcinoma cell lines by preventing protein modifications caused by oxidative stress due to cisplatin treatment, Febs J 275, 390-390.
  11. Telci, D., Basaga, H., Verderio, E. E., Li, X., Tezil, T., Baccarini, M., and Griffin, M. (2006) The RGD-independent signalling pathway in response to fibronectin-tissue transglutaminase complex, Febs J 273, 100-100.
  12. Mehmet Ali Tufekci, Narcin Palavan-Unsal, Nezih Hekim, Damla Arisan, Tugsan Tezil, “Phytotoxicity of hydrogen peroxide: Comparison of phytotoxic response in in vitro and in vivo”, XV FESPB Congress, 17-21, July, 2006, Lyon, France.
  13. Nese Akis, Zeynep Aydin, Tugsan Tezil, Fuat Yagci, Sevim Kahraman. Endothelial Cell Protective Gene Expression. 2nd Modern Drug Discovery & Development Summit Abstract Book, 3, Philadelphia, 2006.
  14. Tugsan Tezil. Determination of toxic effects of hydrogen peroxide via molecular markers in Allium cepa, 9th National Congress of Biology Students, Bolu 2002.