Archive for the 'PhD Activities' Category

Dissertation submission

On the 28/08/2020 I have succesfully defended my PhD thesis by the title “Characterization of the PATZ1 BTB domain”

The thesis defense was attended by my thesis commitee composed by:

Prof. Dr. Batu Erman

Prof. Dr. Canan Atılgan

Prof. Dr. Zehra Sayers

Asst. Prof. Dr. Stefan H. Fuss

Asst. Prof. Dr. Ogün Adebali

Asst. Prof. Dr. Hasan Demirci

Posted by sofiap on Sep 30th 2020 | Filed in PhD Activities | Comments Off on Dissertation submission

Research Articles

  • Piepoli et al., 2020: Structural analysis of the PATZ1 BTB domain homodimer The crystal structures of the PATZ1 BTB domains from mammals and fish contain homodimers. The core dimer conformation of these BTB proteins is dynamically stable, despite the presence of highly flexible regions in the dimerization interface.

 

  • Piepoli et al, 2020: Molecular Biology of SARS-CoV-2 Understanding the molecular and cellular biology of coronaviruses will increase the speed at which therapies can be generated against COVID-19 and other viral diseases.

Posted by sofiap on Jun 3rd 2020 | Filed in PhD Activities | Comments Off on Research Articles

Training courses

Biacore T200 SPR biosensor (GE Healthcare Life Sciences): 8-10 August 2017, Sabanci University

AKTA pure chromatography system (GE Healthcare Life Sciences): July 2017, Sabanci University

 

Posted by sofiap on Sep 12th 2017 | Filed in PhD Activities | Comments Off on Training courses

Academic Experience

Teaching

Graduate Teaching Assistant at Sabanci University for:

  • Cell Biology (BIO332) Fall 2018
  • Biological Function and Structure/Structural Biology (BIO304/BIO 532) Spring 2018
  • Science of Nature I (NS101) 2014 – 2017

Facilitator for Academic Practices and Development (GR501) graduate course at Sabanci University, Fall 2017

Articles, Conference Posters and Presentations

2014: Design of target specific transcription activator-like effectors by free energy perturbation calculations. S.Piepoli, B.Erman, C.Atılgan

– 2. International BAU Drug Design Congress -Bahçeşehir University Istanbul, TR, April

– Biophysical Society Modeling of Biomolecular Systems Interactions, Dynamics, and Allostery Meeting, Istanbul, TR, September

– 2. MC COST Action CM1306 Meeting, Visegrád, HU, September

2015: Analysis on Target specific Transcription Activator-like Effectors by Free Energy Perturbation Calculations and Perturbation-Response Scanning. S.Piepoli, B.Erman, C.Atılgan

– 22. Statistical Physics Days, Istanbul Technical University, Istanbul, TR, June

Analysis of TALE and its Specific Target DNA Interactions by Free Energy Perturbation Calculations and Perturbation-Response Scanning. S.Piepoli, B.Erman, C.Atılgan

– 3. International BAU Drug Design Congress -Bahçeşehir University Istanbul, TR, October

2016:Thermodynamical Constraints Determine the Position Preferences of Critical Amino Acids in TALE DNA Binding Proteins. S.Piepoli, B.Erman, C.Atılgan (to be submitted)

–  23. Statistical Physics Days, Istanbul Technical University, Istanbul, TR, June (invited speaker)

Characterization of PATZ1 protein structure and its interaction with the tumor suppressor protein p53. S.Piepoli

–  The FEBS Journal Special Issue for the 41st FEBS Congress, September (scheduled)

– COST CM1306 Workshop “Lights, Mixing, Action!” Porto, PT, October

2017: The protein structure of the PATZ1 BTB domain reveals new functions.S.Piepoli, A.Alt, E.Mancini, C.Atilgan, B.Erman

–  MolBiyoKon’17, 5th International Congress of the Molecular Biology Association of Turkey, Istanbul, Boğaziçi University, September (poster)

– 5. International BAU Drug Design Congress -Bahçeşehir University Istanbul, TR, October

2018: Function from structure: PATZ1 BTB domain. S. Piepoli, B. Erman, E. Mancini, A. Alt, C. Atilgan (3rd Best Poster Award)

– COST CM1306 4th International Scientific Meeting, Zagreb, HR, March

– 3 Minutes Thesis (3MT) Competition: “Crystals are a girl’s best friend”. Sabanci University, Istanbul, TR, May

– MolBiyoKon’18, 6th International Congress of the Molecular Biology Association of Turkey, Izmir, Biomedicine and Genome Center, September (selected short talk)

2019: Function from Structure: The BTB domain in PATZ1. S. Piepoli

– FENS Research Day, Sabanci University, TR, February (selected speaker)

Additional information

  • Registered User for beamtime at Diamond Light Source since July 2016.
  • Invited speaker at the 23. Statistical Physics Days, Istanbul Technical University, Ayazağa Kampüsü, Istanbul, Turkey, June 2016
  • Participant in the European Cooperation in Science and Technology (COST) Project – CM1306 Action, since September 2014. cost.eu
  • Certificate of Completion of all required training and internship for the Teaching Scholars Residency Program at Sabanci University during 2014-2015 academic year.
  • TOEFL score: 109, July 2014

 

Posted by sofiap on May 16th 2017 | Filed in PhD Activities | Comments Off on Academic Experience