ARTICLES IN REFEREED JOURNALS

  1. Tugce Ayca Tekiner and Huveyda Basaga: Role of microRNA deregulation in breast cancer cell chemoresistance and stemness. Current Medicinal Chemistry, In Press.
  2. Cagri Bodur, Ozgur Kutuk, Gizem Karsli-Uzunbas, Tayirjan T. Isimjan, Paul Harrison,Huveyda Basaga: Pramanicin Analog Induces Apoptosis in Human Colon Cancer Cells: Critical Roles for Bcl-2, Bim, and p38 MAPK Signaling. PLoS ONE, 8, 2,1-13, 2013. Full text
  3. C. Bodur and H. Basaga: Bcl-2 inhibitors; Emerging Drugs in Cancer Therapy, Current Medicinal Chemistry, 19, 1804-1820-2012. Full text
  4. Tugsan Tezil, Cagri Bodur, Ozgur Kutuk, Huveyda Basaga: IKK-B mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death. Cellular Signalling, 24, 1361-1368, 2012. Full text
  5. Cagri Bodur, Ozgur Kutuk, Tugsan Tezil, Huveyda Basaga: ”Inactivation of Bcl-2 through I kappa B kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE). J. of Cellular Physiology, 19, 3556-65, 2012. Full text
  6. Can Timucin , Ozgur Gul, Ozgur Kutuk, Huveyda Basaga: Antibody array based immunosensor for detecting cardiovascular disease markers. J.of Immunoassay and immunochemistry. 33: 275-290, 2012. Full text
  7.  Vurusaner, B., Poli G., Basaga, H.: Tumor suppressor genes and ROS: Complex networks of interactions. Free Rad. Biol. Med. 52: 7-18 (2012). Full text
  8. ANNE NEGRE-SALVAYRE 1 , NATHALIE AUGE 1 , VICTORIA AYALA 2 ,HUVEYDA BASAGA 3 , JORDI BOADA 2 , RAINER BRENKE 4 , SARAH CHAPPLE 5 ,GUY COHEN 6 , JANOS FEHER 7 , TILMAN GRUNE 8 , GABRIELLA LENGYEL 7 ,GIOVANNI E. MANN 5 , REINALD PAMPLONA 2 , GIUSEPPE POLI 9 ,MANUEL PORTERO-OTIN 2 , YAEL RIAHI 6 , ROBERT SALVAYRE 1 , SHLOMO SASSON 6 ,JOSE SERRANO 2 , OFER SHAMNI 6 , WERNER SIEMS 10 , RICHARD C. M. SIOW 5 ,INGRID WISWEDEL 11 , KAMELIJA ZARKOVIC 12 & NEVEN ZARKOVIC 13; Pathological aspects of lipid peroxidation, Free Radical Research,  44(10): 1125?1171; October 2010. Full text
  9. Ozgur Kutuk; Sehime Gulsun Temel; Sahsine Tolunay; Huveyda Basaga; Aven blocks DNA damaged induced apoptosis by stabilizing Bcl-xl. European journal of Cancer. 46: 2494-2505 (2010). Full text
  10. Arisan ED, Kutuk O, Tezil T, Bodur C, Telci D, Basaga H. Small inhibitor of Bcl-2, HA14-1 selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells. Breast Cancer Res Treat. 119:271-281, 2010. Abstract
  11. Telci D, Collighan RJ, Basaga H, Griffin M. Increased TG2 expression can result in induction of TGF{beta}1 causing increased synthesis and deposition of matrix proteins which can be regulated by nitric oxide. J Biol Chem.  VOL. 284, NO. 43, pp. 29547?29558, 2009.
  12. Kutuk, Ozgur; Arisan, Elif; Tezil, Tugsan; Shoshan, Maria; Basaga, Huveyda; Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa mediated lipid peroxidation. Carcinogenesis. vol.30 no.9 pp.1517?1527, 2009.full text
  13. Hernlund E, Kutuk O, Basaga H, Linder S, Panaretakis T, Shoshan M. Cisplatin-induced nitrosylation of p53 prevents its mitochondria translocation. Free Radic Biol Med. 2009 Jun 15;46(12):1607-13. Abstract
  14. Telci D, Li X, Elisabetta A. M. Verderio, Martin Humphries, Huveyda Basaga and Martin Griffin: Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling. J Biol Chem. 283(30):20937-20947, 2008. Abstract
  15. Ozgur Gul, Huveyda Basaga and Ozgur Kutuk. Apoptotic blocks and chemotherapy resistance: Unraveling Bcl-2 protein network. Briefings in Functional Genomics and Proteomics. Feb. 18, 1-8, 2008. Abstract
  16. Gul O, Calay E, Basaga H and Gurbuz Y. Sandwich ? type, Antibody Microarrays for Detection and Quantification of Cardiovascular Risk Markers, Sensors and Actuators B, 125, 581-588, 2007. Abstract
  17. Kutuk O, Basaga H. Apoptosis Signalling by HNE; A Role For JNK-c-Jun/AP-1 pathway. Redox Report, 12: 30-35, 2007. Abstract
  18. Kutuk O and Basaga H. Bcl-2 proteins and vascular apoptosis: Implications in atherosclerosis. Apoptosis, 11, 1661-1671, 2006 . Abstract
  19. Arslan MA, Kutuk O and Basaga H. Protein Kinases as Drug Targets in Cancer, Current Cancer Drug Targets, 6, 623-634, 2006. Abstract
  20. Kutuk O, Poli G and Basaga H. Resveratrol protects against 4-hydoxynonenal induced apoptosis by blocking JNK and c-JUN/AP-1 signaling. Toxicological Sciences, 90(1), 120-132, 2006. Abstract
  21. Arslan MA, Goktuna SI, Kutuk O and Basaga H Signaling pathways as drug targets in cancer. Advances in Molecular Medicine, suppl.vol1, April 2005 (national). Full text
  22. Kutuk O, Pedrech A, Harrison P and Basaga H.:Pramanicin induces apoptosis in Jurkat leukemia cells; a role for JNK, p38 and caspase activation. Apoptosis,10, 597-609, 2005. Abstract
  23. Kutuk O and Basaga H. Aspirin inhibits TNFa- and IL-1-induced NF-kB activation and sensitizes HeLa cells to apoptosis. Cytokine, 25(5), 229-237, 2004. Abstract
  24. Kutuk O and Basaga H. Inflammation meets oxidation: NF-kappa B as a mediator of initial lesion development in atherosclerosis. Trends in Molecular Medicine, vol 9 no12, 548-557, 2003. Abstract
  25. Kutuk O, Adlı M, Poli G and Basaga H. Resveratrol protects against 4-hydroxynonenal-induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts. Biofactors,20,1-10, 2004. Abstract
  26. Kutuk O and Basaga H. Aspirin prevents apoptosis and NF-kB activation induced by H2O2 in HeLa cells. Free Radical Research. vol 37 no 12, 1267-1276, 2003. Abstract
  27. Arkan MC, Leonarduzzi G, Biasi F, Basaga H and Poli G. Physiological amounts of ascorbate potentiate phorbol ester induced nuclear binding of AP-1 transcription factor in cells of macrophagic lineage. Free Radicals in Biology and Medicine, vol. 31, no 3: 374-382, 2001. Abstract
  28. Leonarduzzi G, Sevanian A, Sottero B, Arkan MC, Biasi F, Chiarpotto E, Basaga H and Poli G. Up-regulation of the fibrogenic cytokine TGF-ß by oxysterols: A mechanistic link between cholesterol and atherosclerosis. FASEB Journal, 15, 1619-1622, 2001. Full text
  29. Leonarduzzi G, Arkan C, Basaga H, Chiaropotto A, Sevanian E, Poli G. Lipid Oxidation products in cell signaling. Free radicals in Biology and Medicine, 28, 9,1370-1378, 2000. Abstract
  30. Onat D, Bosciboinik D, Azzi A, Basaga H. Effect of alpha-tocopherol and silibin dihemisuccinate on the proliferation of human skin fibroblasts. Biotechnol.Appl. Biochem. 29, 213-215, 1999. Abstract
  31. Basaga HS, Poli G, Tekkaya C and Aras I. Free radical scavengingand antioxidative properties silibin complexes on microsomal lipid peroxidation. Cell Biochem. and Function. 15: 27-33, 1997. Abstract
  32. Basaga HS, Tekkaya C and Açikel F. Antioxidative and free radical scavenging properties of rosemary extract. J. Food Science and Technology. 30, 105-108, 1997.
  33. Basaga HS, Dik T. Effect of lactoperoxidase system on the activity of starter culture for yogurt production. Milchwissenschaft, 49: 3, 144-147, 1994.
  34. Basaga HS, Geban Ö, Tekkaya C. The effect of instruction supplied with inquiry approach on biochemistry and science process skill achievements. Biochem. Ed. 22, 1, 29-32, 1994.
  35. Poli G, Carini R, Comoglio A, Basaga HS, Albano E. Antioxidant and free radical scavenging properties of IdB 1016, a new flavanolignan complex. Eicosanoids and other bioactive lipids in cancer edited by Santoch Nigam, Lawrence J. Marnett, Kenneth V. Honn, Thomas L. Walden. Kluwer Academic Publishers, 1992.
  36. Comoglio A, Leonarduzzi G, Carini R, Bussolin D, Basaga HS, Albano E, Tomassi A, Poli G, Morazzoni P and Magistretti MJ. Studies on the antioxidant and free radical scavenging properties of IdB 1016; a new flavanolignan complex. Free Rad. Res. Comms. 11, 109-115, 1990. Abstract
  37. Basaga HS. Biochemical aspects of free radicals. Biochem.Cell Biol.68, 989-998, 1990. Abstract
  38. Basaga HS. Free radical inactivation of proteins and protection by antioxidants. Turkish J. of Biochem. 3, 25-33, 1987.
  39. Bahnemann D, Basaga HS, Dunlop JR, Searle AJF, Willson RL. Metronidazole, Misonidazole, iron, zinc and sulfur compounds in cancer. Brit.J. of Cancer, 37 supp. III, 14-17, 1978. Abstract
  40. Basaga HS, Dunlop JR, Searle AJF, Willson RL. Metronidazole, Misonidazole, reduction by facultative anaerobes and cytotoxic action on hypoxic bacteria and mammalian cells in vivo. Brit. J. of Cancer, 37 Supp. III, 132-138, 1978.

BOOK CHAPTERS

  1. Ozgur Kutuk and Huveyda Basaga. ?Apoptotic pathways in mitochondria? in Modern insights into disease from into insights into disease from molecules to man. Editor: Victor R. Preedy. 2009.
  2. Ozgur Kutuk, Dilek Telci and Huveyda Basaga. ?Lipid peroxidation, gene expression and resveratrol; implications in atherosclerosis? in Phytochemicals, CRC Press. 2006.pp 61-82. Eds. Dr. Mark Meskin, Dr. Wayne Bidlack and Dr. Keith Randolph
  3. Ozgur Kutuk and Huveyda Basaga. ?Phytoestrogens in cell signaling? in Phytoestrogens in Functional Foods, Taylor & Francis. October, 2005. pp 123-152. Eds. Yıldız F.,/Adlercreutz H.

REPORTS

  1. TUSIAD ? Competitiveness strategies: Biotechnology report. December 2005.
  2. TUSIAD ? Competitiveness strategies: Biotechnology report. March ? December, 2000.

PROCEEDINGS

  1. Bodur C, Kutuk O, Poli G, Basaga H.: Role of Bcl-2 protein family members in 4-hydroxynonenal mediated apoptosis , Annual Meeting of the Society-for-Free-Radical-Research – Europe, AUG 26-29, 2009 Rome, Italy. Free Radical Research, 43, 34-34 Suppl. 1, 2009.
  2. Gul O, Inceturkmen E, Kutuk O, Basaga H, Sezerman U and Gurbuz Y. Biosensor Implementation for Cardiovascular Risk Marker Analysis, IEEE Conference on Sensors, 2005.
  3. Arkan M.C., Leonarduzzi G., Biasi F., Basaga H and Poli G. Ascorbate enhances PMA induced DNA binding of AP-1 through MAPK pathway. Proceedings of 11th Biannual meeting of SFRR Paris, France, July 16-22, 2002.
  4. Kutuk O and Basaga H. ?Modulation of H2O2 and TNF-alpha induced Nf-KB activation by acetylsalicylic acid (Aspirin)? Proceedings of 11th Biannual meeting of SFRR Paris, France, July 16-22, 2002.