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Javed H. Niazi KM

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Biosensors & Biomolecular Technology Lab at SUNUM

Javed H. Niazi (Kolkar)

"Our work spans from cellular and molecular engineering and electrochemistry to bio-inspired synthetic bio-/nano-materials that are targeted toward designing analytical reagents and biosensors with recognition and signal transduction capabilities"


Research Interests

Design and development of novel assays for biosensor applications-mainly for early warning and diagnosis of cardiovascular and cancer diseases

In-vitro selection and modification of synthetic ssDNA/RNA aptamers as affinity ligands for disease biomarkers and drugs

Aptamer-fascilitated biomarker discovery

ssDNA/RNA aptamer directed nano-material/vesicle mediated targeted drug-delivery and/or imaging

Nanotoxicology & Green nanotechnology


Current Research

Click here--> https://www.youtube.com/watch?v=dX9tWtyG8Iw&feature=youtu.be

Research highlights

(1) Electrical biosensing of foodborne pathogenic bacteria down to 10 cells/mL.

(2) E-cigarettes smoke likely to cause DNA-damage!

(3) Quantum dot decorated whole-bacterial cells as fluorescent reporters to probe cellular damages.

(4) Aptamers as biorecognition elements for cancer detection.

(5) Microbial catalysis of engineered nanomaterials.

Research areas

(1) Synthetic ssDNA aptamers as affinity ligands for cancer biomarkers.

(2) Decorating living cell-surfaces with quantum dots for probing cellular dynamics.

(3) Design and development of biosensors for biomedical and environmental applications.

(4) Microbial catalysis of engineered nanomaterials.

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